|Classification and external resources|
Tonsil biopsy in variant CJD. Prion protein immunostaining.
Creutzfeldt-Jakob disease (/ / KROITS-felt YAH-kohb) or CJD is an incurable disease of the human brain. It is caused by special proteins called prions, and it always leads to death. There are different versions of the disease. Some have genetic origins, others have been acquired by coming into contact with infected tissue. There is about one case per year, per million inhabitants.
German neurologist Hans Gerhard Creutzfeldt first described the disease in 1920. Shortly after Creutzfeldt, Alfons Maria Jakob also described the disease, so that it is called Creutzfeldt–Jakob today.
References[change | change source]
- Merriam-Webster's Collegiate Dictionary
- "CJD (Creutzfeldt-Jakob Disease, Classic)". Centers for Disease Control and Prevention. 2008-02-26. http://www.cdc.gov/ncidod/dvrd/cjd/index.htm. Retrieved 2009-06-20.
- Meggendorfer F. Klinische und genealogische Beobachtungen bei einem Fall von spastischer Pseudokosklerose Jakobs. Z Neurol Psychiatry 1930; 128: 337–41
- Gambetti P, Kong Q, Zou W, Parchi P, Chen SG. Sporadic and familial CJD: classification and characterisation. British Medical Bulletin 2003;66:213-39. PMID 14522861
Other websits[change | change source]
- UCSF Memory and Aging Center - education website from a CJD patient care and research center
- UCSF Memory and Aging Center YouTube channel with movies about CJD
- Institute for Neurodegenerative Diseases (IND) - a basic science research institute working on a cure for CJD
- Creutzfeldt-Jakob Disease at the Open Directory Project