Eloise Gwendolyn Sanford (also known as Isabel Sanford; August 29, 1917 - July 9, 2004) was an American movie, television and stage actress. She starred in several notable sitcoms. She played Louise "Weezy" Jefferson in The Jeffersons (January 1975 - June 1985). She also had many movie roles. Sanford was born in Harlem, New York; the actress died in Los Angeles due to natural causes at age eighty six.