Talk:Gas chromatography–mass spectrometry

Just making the note, please don't delete the page. I will go through it and work on it. -Barras (talk) 09:50, 4 August 2011 (UTC)[reply]

substances needs linking. - done
Is there a better word for Applications. It actually links to a disambig page. - done
airport probably needs a link. - done
luggage is not simple. - linked
human beings needs linking. - done
disintegrated is not simple. - done
merely is not simple. - done
statistically needs linking. - done
machine needs linking. - done
sensitive devices is not simple. - done
fragile is not simple. - linked
graph paper should be linked (even if redlinked, this was often used years ago) - for example, Doug Mink's discovery of the rings around Uranus was originally captured on graph paper that is now hung in the Smithsonian's Air & Space Museum. Done.
attached is not simple. - done
computers needs linking. - done
discovery needs linking. - done
In 1964, Electronic Associates, Inc. (EAI), a leading U.S. supplier of analog computers, began development of a computer controlled mass spectrometer[3] under the direction of Robert E. Finnigan. should be split up into two or maybe three sentences. - done
is used and mixed are passive. - not quite, mixed is not passive.
is dissolved is passive and needs linking. - done
is injected is passive and probably not really simple. - done
coating needs a link. - done
electric charge needs linking. - done
weight needs linking. - done
library needs linking. - done

This is only until the basic operation section. Will do later more. -Barras (talk) 20:46, 3 September 2011 (UTC)[reply]

properties could use a link. - done
The molecules take different amounts of time (called the retention time) to come out of (elute from) the gas chromatograph, and this allows the mass spectrometer downstream to capture, ionize, accelerate, deflect, and detect the ionized molecules separately. is too long. - done
ratio should be linked. - done
degree is not simple in this context.
The mass spectrometry process normally requires a very pure sample while gas chromatography using a traditional detector (e.g. Flame Ionization Detector) detects multiple molecules that happen to take the same amount of time to travel through the column (i.e. have the same retention time) which results in two or more molecules to co-elute is too long and complex. - done
mass spectrum could probably be linked. - done
Combining the two processes reduces the possibility of error, as it is extremely unlikely that two different molecules will behave in the same way in both a gas chromatograph and a mass spectrometer. should be split up into two sentences. - done
certainty is not simple as probably the whole sentence around. - done
referred to by the is not simple. This sentence needs to be rephrased probably. - done
magnetic needs linking. - done
bulky is not simple. - done
encountered is not simple. - done
utilized needs a link. - done
collecting needs linking. - done
fragments and determined are not simple. - done
dictated is not simple. - done
anticipates is not simple. - done
cognizant is not simple. - done
interferences is not simple. - done
nitrogen, carbon, dioxide needs linking. - done
Additionally if one is to use a large scan range then sensitivity of the instrument is decreased due to performing fewer scans per second since each scan will have to detect a wide range of mass fragments. is too long. - done
confirming or resolving need both linking. done
During instrument method development it may be common to first analyze test solutions in full scan mode to determine the retention time and the mass fragment fingerprint before moving to a SIM instrument method. is too long. - done
entered not simple in this context. - done
likelihood is not simple. - done
potentially is probably not simple. -done
To additionally confirm the likelihood of a potentially positive result, it is relatively important to be sure that the ion ratios of the various mass fragments are comparable to a known reference standard. is a bit long. - reworded
After the molecules travel the length of the column, pass through the transfer line and enter into the mass spectrometer they are ionized by various methods with typically only one method being used at any given time. is too long. - done
diode needs linking. - done
By far at the start of the sentence makes it more complex and is unneeded. - done
bombarded is not simple. - done
The molecules enter into the MS (the source is a quadrupole or the ion trap itself in an ion trap MS) where they are bombarded with free electrons emitted from a filament, not much unlike the filament one would find in a standard light bulb. is too long. - done
characteristic needs linking. - done
reproducible is not simple. - done
approaching is not simple. - done
colliding is not simple. - done
eV (electron Volts) needs linking. - done
facilitates is not simple. - done
The use of 70 eV facilitates comparison of generated spectra with library spectra using manufacturer-supplied software or software developed by the National Institute of Standards (NIST-USA). is too long and complex. - done
Spectral library searches employ matching algorithms such as Probability Based Matching[5] and dot-product[6] matching that are used with methods of analysis written by many method standardization agencies. is too long. - done
Depending on the technique (positive CI or negative CI) chosen, this reagent gas will interact with the electrons and analyte and cause a 'soft' ionization of the molecule of interest. is quite long. - done
One of the main benefits of using chemical ionization is that one of the mass fragment has a weight closely corresponding to the molecular weight of the analyte of interest. is quite long. - done
proton needs linking (if not already done earlier in the article. - done
amounts needs linking. - done
decreases needs a link (to wikt) - done
supply needs linking. - done
(The fragments don't break up further.) please don't use abbreviations. - done
quantify needs linking. - replaced word
concentrations needs linking. - done
comparative link? - done
myriad is not simple. - done
visual distortions both words need linking. - done
scale needs linking. - done
simultaneously is not really simple. - dropped
correlate is not simple. - done
peaks needs linking. - done
assigned is not really simple. - done
being assigned is not simple language. - done
proportionate is not simple. - done
unique needs linking. - done
has been matched is not simple language. - not found
Once a chemical formula has been matched to the spectrum, the molecular structure and bonding can be identified, and must be consistent with the characteristics recorded by GC-MS. is quite long. - done
this identification done automatically <- I'm not sure, but is there an is missing? - yes
Conversely is not simple. - done
assumption is not simple. - done
MS/MS can sometimes be used to measure the amount of low levels of target compounds in the presence of a high sample matrix background. sounds somehow complex. - done
being performed is not simple language.
precursor is not simple.
Types of analysis include product ion scan, precursor ion scan, Selected Reaction Monitoring (SRM) (sometimes referred to as Multiple Reaction Monitoring (MRM)) and Neutral Loss Scan. is quite long.
prominent product isn't really simple in this context.
is becoming is not really a simple phrase. - done
choice needs linking. - done
tracking is not really simple. - done
environment needs linking. - done
significantly there are probably easier words for this.
The cost of GC-MS equipment has decreased significantly, and the reliability has increased at the same time, which has contributed to its increased adoption in environmental studies. this can probably be split up into two sentences. - done
pesticides and herbicides needs linking. - done
debris is not simple. - done
American Society for Testing Materials sounds important enough for a link. - done
court could use a link. - done
increasingly is not simple. - dropped
narcotics needs linking. - done
supplant needs linking. - done
dogs needs linking. - done
toxicology needs linking. - done
poisons needs linking. - done
biological specimens of suspects, victims, or the deceased links. - done
These systems run on a host of technologies, many of them based on GC-MS. There are only three manufacturers certified by the FAA to provide these systems, one of which is Thermo Detection (formerly Thermedics), which produces the EGIS, a GC-MS-based line of explosives detectors. is too long. - done
Check the links for esters, fatty acids, alcohols, aldehydes, terpenes, I bet that some at least exist here. - singular links
spoilage needs linking. - done
governmental agencies needs linking. - done
congenital is not simple. - done
metabolic diseases both needs linking. - done
newborn link. - done

In general, sentences that cover more than one line are usually too long and should if possible be split up. We link most substantives, when they are useful to link. You use many adverbs in the text, while this sounds often great, it makes the text more complex. Remove those words if they are not needed. I think that's all now for this article. -Barras (talk) 10:39, 5 September 2011 (UTC)[reply]

Big sentences[change source]

I've just finished reading the article again. You've done a really good work here, however, I just found some more things. Those sentences should be tried to be shortened:

Gas chromatography using a traditional detector (e.g. Flame Ionization Detector) detects multiple molecules that happen to take the same amount of time to travel through the column (that is, have the same retention time) which results in two or more molecules to co-elute. - done
Types of analysis include product ion scan, precursor ion scan, Selected Reaction Monitoring (SRM) (sometimes referred to as Multiple Reaction Monitoring (MRM)) and Neutral Loss Scan. especially the stuff in the brackets makes this sentence quite long. - done
So, SIM analysis allows for a smaller quantity of a compound to be detected and measured, but the degree of certainty about the identity of that compound is reduced. - done
This "hard ionization" technique results in the creation of more fragments of low mass to charge ratio (m/z) and few, if any, fragments having a mass near the mass of the original molecule. - done
The other two manufacturers are Barringer Technologies, now owned by Smith's Detection Systems, and Ion Track Instruments, part of General Electric Infrastructure Security Systems. - done
It is also used to detect and measure contaminants from spoilage or adulteration which may be harmful and which is often controlled by governmental agencies, for example pesticides. - done
Therefore, when an identifying mass spectrum appears at a characteristic retention time in a GC-MS analysis, it typically lends to increased confidence that the analyte of interest is in the sample. - done
Most applications are based on the use of 13C as the labeling and the measurement of 13C-12C ratios with an isotope ratio mass spectrometer (IRMS); an MS with a detector designed to measure a few select ions and return values as ratios. - done
Typically, this identification is done automatically by computer programs which come with the instrument, given a list of the elements which could be present in the sample. - done
A MS should not be set to look for mass fragments too low or else one may detect air (found as m/z 28 due to nitrogen), carbon dioxide (m/z 44) or other possible interferring factors. - done
This is a fast and efficient analysis, especially if the analyst has previous information about a sample or is only looking for a few specific substances. - done
To improve the chances of reading a positive result correctly, it is important that the ion ratios of the various mass fragments are comparable to a known reference standard. - done
The isotope pattern in the spectrum, which is unique for elements that have many isotopes, can also be used to identify the various elements present. the part in the middle makes this one a bit long. - done
This is an increasingly becoming a common way to diagnose IEM for earlier diagnosis and institution of treatment eventually leading to a better outcome. - done

That's all I found now while reading it again, but you really did some good work in simplifying here! Sorry that those sentences above are not in the same order as they are in the article, I got some help to find them. -Barras (talk) 08:53, 7 September 2011 (UTC)[reply]