Fertility

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Fertility is the natural capability to give life. In humans and animals, fertility means that the parent can produce babies.

More precisely, fertility is the capacity of an individual or population to produce viable offspring.[1] By 'viable' is meant 'able to live and reproduce'.

In agriculture, fertility means that a soil can support the growth of plants because it contains the right minerals and nutrients.

Fertility can also be used as a metaphor: having a "fertile imagination" means being able to think of many new and interesting things.

As a measure, fertility rate is the number of children born per couple, or person or population. This is different to fecundity. This is defined as the potential for reproduction (influenced by gamete production, fertilisation and carrying a pregnancy to term. In English language, the term was originally applied only to females, but increasingly is applied to males as well, as common understanding of reproductive mechanisms increases and the importance of the male role is better known. Infertility is a deficient fertility.

Human fertility depends on factors of nutrition, sexual behavior, culture, instinct, endocrinology, timing, economics, way of life, and emotions. Animal fertility is no less complex, and may display astounding mechanisms.

Human fertility[change | change source]

Female Fertility[change | change source]

In the United States, the average age of menarche (first period) is about 12.5 years.[2] However, in most girls, menarche does not signal that ovulation has occurred. In postmenarchal girls, about 80% of the cycles are anovulatory in the first year after menarche, 50% in the third and 10% in the sixth year.[3] Women's fertility peaks between ages 22–26, and after 35 it starts to sharply decline.

Birth rates have been noted by Henri Leridon, PhD, as an epidemiologist with the French Institute of Health and Medical Research. Of women trying to get pregnant, without using fertility drugs or in vitro fertilization:

  • At age 30
    • 75% will have a conception ending in a live birth within one year
    • 91% will have a conception ending in a live birth within four years.
  • At age 35
    • 66% will have a conception ending in a live birth within one year
    • 84% will have a conception ending in a live birth within four years.
  • At age 40
    • 44% will have a conception ending in a live birth within one year
    • 64% will have a conception ending in a live birth within four years.[4][5]

The use of fertility drugs and/or in vitro fertilization can increase the chances of becoming pregnant at a later age.[6]

Male Fertility[change | change source]

There is evidence that male reproduction abilities are reduced with higher age.[7] Sperm count is becoming smaller with age, with men aged 50–80 years producing 75% of sperm compared with 20–50 years old males. If the sperm count is too low, a man could increase it with herbal and chemical supplements.[8] Even larger change can be seen in the number of seminiferous tubules produced by males at different age stages:

  • In males 20–39 years old, 90% of the seminiferous tubules contain mature sperm.
  • In males 40–69 years old, 50% of the seminiferous tubules contain mature sperm.
  • In males 80 years old and older, 10% of the seminiferous tubules contain mature sperm.[9]

Male infertility treatment[change | change source]

Treatment depends on what is causing infertility. Many problems can be cured with medicines or surgery. This will allow conception through normal sex. The treatments below are divided into 3 categories.[10]

  • Non-surgical (Medical) Therapy- Antibiotics to treat infections (may not restore fertility) Hormone Replacement Therapy to correct hormonal imbalance Anti-Oxidants in high ROS (reactive oxygen species)- debatable.
  • Surgery- Varicocelectomy, Vasovasostomy, Vasoepididymostomy TUR (trans-urethral resection) in ejaculatory duct obstruction Surgical sperm retrieval (TESA, TESE, PESA, MESA)
  • Assisted Reproduction Techniques- IUI, IVF, ICSI- increases the chances of fertilization in men suffering from infertility Use of donor sperm sample recommended as last resort and can be used depending on the couple's wish.[11]

Infertility[change | change source]

When a person is infertile it means that they are unable to have a child naturally. Infertility is define as the inability to fall pregnant or carry a pregnancy until birth after 12 months or more of unprotected sex. About 10% of people are infertile. This means that 1 in 10 people will not be able to conceive a child naturally. There are many causes of infertility some of them can be treated.[12] As a woman gets older, her fertility declines. After menopause a woman is no longer fertile.

References[change | change source]

  1. King R.C. et al. (2006). A Dictionary of genetics. 7th ed, Oxford University Press. p. 234
  2. Anderson SE, Dallal GE, Must A (April 2003). "Relative weight and race influence average age at menarche: results from two nationally representative surveys of US girls studied 25 years apart". Pediatrics. 111 (4 Pt 1): 844–50. doi:10.1542/peds.111.4.844. PMID 12671122.CS1 maint: multiple names: authors list (link)
  3. Apter D (Feb 1980). "Serum steroids and pituitary hormones in female puberty: a partly longitudinal study". Clinical Endocrinology. 12 (2): 107–20. doi:10.1111/j.1365-2265.1980.tb02125.x. PMID 6249519.
  4. http://www.ingentaconnect.com/content/oup/humrep/2004/00000019/00000007/art01548
  5. Leridon, Henri (1 July 2004). "Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessment". Human Reproduction. 19 (7): 1548–1553. doi:10.1093/humrep/deh304 – via academic.oup.com.
  6. "Spanish woman 'is oldest mother'". BBC News. 30 December 2006. Retrieved 2006-12-30.
  7. Kidd SA, Eskenazi B, Wyrobek AJ (Feb 2001). "Effects of male age on semen quality and fertility: a review of the literature". Fertil. Steril. 75 (2): 237–48. doi:10.1016/S0015-0282(00)01679-4. PMID 11172821.CS1 maint: multiple names: authors list (link)
  8. Male fertility supplement Archived 2013-03-23 at the Wayback Machine website
  9. Effect of Age on Male Fertility Seminars in Reproductive Endocrinology. Volume, Number 3, August 1991. Sherman J. Silber, M.D.
  10. "Male Infertility Treatment – Fertility Treatment for Men". IVF. Retrieved 2021-08-07.
  11. "Male Infertility Clinic - Symptoms, Causes, Treatment and Prevention". gunjanivfworld. Retrieved 2021-08-07.
  12. Makar RS, Toth TL (2002). "The evaluation of infertility". Am J Clin Pathol. 117 Suppl: S95–103. PMID 14569805.

Further reading[change | change source]

  • Bock, J. (2002). Evolutionary Theory and the search for a unified theory of fertility. American Journal of Human Biology. 14(2) 145–148. Full text