František Derfler (12 November 1942 – 17 August 2019) was a Czech actor, educator and political activist. He was born in Prague. He was a professor of divisions. In November 1989 he co-founded the local Civic Forum in Brno and became its spokesperson. He was one of the signers of Charter 77.
Derfler died on 17 August 2019 in Prague at the age of 76.