IPSA may mean:
- I. P. Sharp Associates, Canadian company, creator of the IPSANET computer network
- Independent Parliamentary Standards Authority, a public body in the United Kingdom
- Indice de Precio Selectivo de Acciones, Chilean Stock Index
- International Political Science Association, UNESCO scholarly association
- Institut Polytechnique des Sciences Avancées, French private grande école in aeronautical and space engineering
- Intimate partner sexual assault, a variant term for spousal rape
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