Irene Fernandez (1 June 1946 – 31 March 2014) was a Malaysian human rights activist. She was a PKR supreme council member. She was the director and co-founder of the non-governmental organization Tenaganita. She helped the rights of migrant workers and other oppressed and poor people in Malaysia. She was arrested in 1996 and charged with 'maliciously publishing false news'.
She died on 31 March 2014 of heart failure.