Molecular subtypes

From Simple English Wikipedia, the free encyclopedia

Molecular subtyping of cancer, as its name suggests, is a new way to classify cancers into different groups based on molecular data and classification models. Unlike the traditional histological classification of cancer, molecular classifications rely on biomarkers and classifiers. Biomarkers can be informative genes, microRNAs (miRNAs), DNA methylation markers and others. Classifiers can be built by machine learning algorithms, such as Prediction Analysis for Microarrays (PAM), Support Vector Machines (SVMs) and more.[1]

References[change | change source]

  1. Zhao, L; Lee, VHF; Ng, MK; Yan, H; Bijlsma, MF (25 March 2019). "Molecular subtyping of cancer: current status and moving toward clinical applications". Briefings in Bioinformatics. 20 (2): 572–584. doi:10.1093/bib/bby026. PMID 29659698. Retrieved 14 July 2022.