Santa Cruz might mean:
Settlements[change | change source]
- Santa Cruz, Bolivia, the largest city in Bolivia
- Santa Cruz, California, and city in the U.S. state of California
- Santa Cruz, Chile, a commune in Chile
- Santa Cruz, Trinidad and Tobago
- Santa Cruz de Barahona, a city in the Dominican Republic
- Santa Cruz de Tenerife, capital of the Canary Islands
Other[change | change source]
- Santa Cruz del Seibo, a city in the Dominican Republic
- Santa Cruz Province, Argentina
- Santa Cruz River, a river in Arizona, United States and Sonora, Mexico
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