Tezcatlipoca may also mean:
- Tezcatlipoca (DC Comics), a fictional character from the DC Comics universe and a recurring character in the Wonder Woman series, based on the Aztec god.
- Tezcatlipoca, a villain from DC Comics whom originally believed himself to be Tezcatlipoca incarnate.
- Tezcatlipoca (Los Comex), a character from the independent comic, El Muerto: The Aztec Zombie.
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