Warfarin

From Simple English Wikipedia, the free encyclopedia

Warfarin (sometimes sold as Coumadin) is a powerful water-soluble compound. It prevents blood from clotting. It does that by reducing the production of factors by the liver that promote clotting. It is called an "anticoagulant agent". It is a powerful rat poison. In concentrated form, it causes bleeding of internal organs which leads to death.[1]

It is also used, in very low doses, to prevent thrombosis in humans.[2] This is the local coagulation or clotting of the blood in the circulatory system. In such cases, it makes heart attacks, strokes, and pulmonary embolism less likely.[2] The degree of anticoagulation is monitored by blood tests.

References[change | change source]

  1. Tornkvist, Max; Smith, J. Gustav; Labaf, Ashkan (2018-02-01). "Current evidence of oral anticoagulant reversal: A systematic review". Thrombosis Research. 162: 22–31. doi:10.1016/j.thromres.2017.12.003. ISSN 0049-3848. PMID 29258056.
  2. 2.0 2.1 "Warfarin Monograph for Professionals". Drugs.com. Retrieved 2022-11-14.