Aspirin
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Aspirin
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| Systematic (IUPAC) name | |
| 2-acetoxybenzoic acid | |
| Identifiers | |
| CAS number | 50-78-2 |
| ATC code | A01AD05 B01, N02 |
| PubChem | 2244 |
| DrugBank | APRD00264 |
| ChemSpider | 2157 |
| Chemical data | |
| Formula | C9H8O4 |
| Mol. mass | 180.157 g/mol |
| SMILES | eMolecules & PubChem |
| Synonyms | 2-acetyloxybenzoic acid acetylsalicylate acetylsalicylic acid O-acetylsalicylic acid |
| Physical data | |
| Density | 1.40 g/cm³ |
| Melt. point | 135 °C (275 °F) |
| Boiling point | 140 °C (284 °F) (decomposes) |
| Solubility in water | 3 mg/mL (20 °C) |
| Pharmacokinetic data | |
| Bioavailability | Rapidly and completely absorbed |
| Protein binding | 99.6% |
| Metabolism | Hepatic |
| Half life | 300–650 mg dose: 3.1–3.2 h 1 g dose: 5 h 2 g dose: 9 h |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status | |
| Routes | Most commonly oral. Lysine acetylsalicylate may be given IV or IM |
Aspirin is a brand name of Acetylsalicylic acid (ASA). It has many uses, but is most commonly used as a pain killer, or used to reduce Fever or Inflammation. It also has an Anti-Platelet effect - it reduces the number of Platelets in the blood which reduces blood clotting- in that function it is used to prevent Heart Attacks.
There are some possible side-effects to this drug. For example, large amounts can damage the kidneys. Children taking aspirin can develop Reye's syndrome which causes the liver to become fatty and not work properly and also the brain to become enlarged. Reyes Syndrome can be fatal, however most children survive it with treatment.
People with lung, kidney disease, Gout, Hyperuricemia (high amounts of Uric Acid in the blood), Hemophilia (a blood clotting disorder), Diabetes or high blood pressure should not take aspirin except on the advice of a qualified medical professional. Nor should people who are allergic to it, to Ibuprofen or to Naproxen. People with Asthma where attacks are brought about by aspirin should avoid using any Anti-inflammatory drugs based on it.
Bayer has a trademark on the brand name aspirin in 80 countries. But in other countries, aspirin is the common name for the drug.
