The English used in this article may not be easy for everybody to understand. (January 2017)
Autoimunity is immune reaction against self components, which are recognized as antigens. This reaction can produce severe inflammation or can be innocuous, as when directed to intracellular autoantigens, which are not expressed to circulating antibodies or to the lymphocytes.
Autoimunity can develop spontaneously or can be induced experimentally by immunization with autoantigens or antigensd croos-reactive with autoantigens. Autoimunity reactions cause numerous autoimmune diseases and disorders.