Azoximer bromide

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Azoximer bromide
Azoximer bromide.svg
Clinical data
SynonymsPolyoxidonium, Synpol
ATC code
Pharmacokinetic data
Bioavailabilityup to 89%
Elimination half-life25.4 hours (intravenous routes)
Identifiers
  • Poly[[1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide]ethylene- co-[(piperazin-1,4-diyl 1-oxide)ethylene]]
CAS Number
ChemSpider
  • none
Chemical and physical data
Formula[[C8H15BrN2O2]x[C6H12N2O]y]n
Molar mass60000–100000 g/mol

Azoximer bromide is a macromolecular compound with high-molecular weight and not proved immunomodulating activity. It is using in CIS countries for treatment and prophylaxis of diseases connected with damage of immune system. It is a N-oxidized polyethylene–piperazine derivative. Azoximer bromide is sold under the trade name Polyoxidonium.

Polyoxidonium is registered in US Patent-5503830 from 1996,[1][2][3] in the Russian Federation from 1996, under registration number 96/302/9, FS 42-3906-00.[4]

References[change | change source]

  1. http://www.google.com/patents/about?id=s9cfAAAAEBAJ&dq=US+5503830
  2. http://www.wikipatents.com/US-Patent-5503830/compounds-having-immunostimulating-activity-and-methods-of-use-thereof[permanent dead link]
  3. http://www.freepatentsonline.com/EP0789586.html
  4. State Scientific Centre of Russian federation, Immunological Institute of Russian Federation Health Resort, CLINICAL ASPECTS OF USE OF IMMUNOMODULATOR POLYOXIDONIUM, Methodical handbook for doctors issued by State Scientific Centre of Russian Federation – Immunological Institute of Russian Federation Health Resort Moscow – 2003