Capsule

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Capsules used for medicine
Cod liver oil soft gel capsules

A pharmaceutical capsule is an easy way to take medication. Capsules may contain powder, liquid or oil.[1] The outer shell is made of hard or soft gelatin. Capsules come in different shapes and colors to identify dose or what company made them.[1] They are also available as timed release which work over a period of time. Capsules should usually be taken whole. Always consult a pharmacist or desk reference before opening a capsule. Capsules should also not be crushed without first checking to see if it is safe.[2]

References[change | change source]

  1. 1.0 1.1 Deborah Gray Morris, Calculate with Confidence, Sixth Edition (London; Amsterdam: Elsevier, 2014), p. 291
  2. Vicki Niblett, A Nurse's Guide to Dosage Calculation: Giving Medications Safely (Philadelphia: Lippincott Williams & Wilkins, 2006), p. 129

INFORMATION ABOUT SOFT GELATIN CAPSULE


Soft gelatin capsules, also known as softgels or soft elastic capsules, are hermetically sealed one-piece capsules containing a liquid or a semisolid fill without a bubble of air or gas. They are made from a more flexible, gelatin film plasticized by the addition of glycerine, sorbitol, .

As with hard gelatin capsules, soft gelatin capsules are predominantly administered orally. Some can be formulated and manufactured to produce a number of different drug delivery systems such as

a.    Chewable softgels where a highly-flavoured shell is chewed to release the drug liquid fill matrix

b.    Suckable softgels which consist of a gelatin shell containing the flavoured medicament to be sucked and a liquid matrix (or just air inside the capsule)

c.    Twist-off softgels which are designed with a tag to be twisted or snipped off, thereby allowing access to the fill material and

d.    Meltable softgels designed for use as pessaries or suppositories.

References

·        Allen L. and Ansel H. (2014). Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. Philadelphia: Lipincott Williams and Wilkins.

·        Augsburger, L and Hoag, S. (2018). Pharmaceutical Dosage Forms: Capsules. New York: Taylor & Francis Group.

·        Aulton, M. and Taylor, K. (2013). Aulton’s Pharmaceutics: The Design and Manufacture of Medicines, (4th ed.). Edinburgh: Churchill Livingstone.

·        Dash, A., Singh, S. and Tolman, J. (2014). Pharmaceutics – Basic Principles and Application to Pharmacy Practice. USA: Academic Press.

·        Felton, L. (2012). Remington Essentials of Pharmaceutics. UK: Pharmaceutical press.

·        Ghosh, T. and Jasti, B. (2005). Theory and Practice of Contemporary Pharmaceutics. USA: CRC Press LLC.

·        Gibson, M. (2009). Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form. New York: Taylor & Francis Group.

·        Hoag, S. (2017). Capsules Dosage Form: Formulation and Manufacturing Considerations. In Y. Qui, Y. Chen, G. Zhang, L. Yu, and R. Mantri (Eds.), Developing Solid Oral Dosage Forms – Pharmaceutical Theory and Practice, (2nd ed.) (pp. 723-747). UK: Elsevier Inc.

·        Jones D. (2008). Fasttrack Pharmaceutics – Dosage Form and Design. London: Pharmaceutical Press.

·        Lachman, L., Lieberman, H. and Kangi, J. (1990). The Theory and Practice of Industrial Pharmacy (3rd ed.). USA: Lea & Febiger.

·        Liu, R. (2018). Water-Insoluble Drug Formulation (3rd ed.). New York: Taylor & Francis Group.

·        Mahato, R. and Narang, A. (2018). Pharmaceutical Dosage Forms and Drug Delivery (3rd ed.). New York: Taylor & Francis Group.

·        Ofoefule, S. (2002). Textbook of Pharmaceutical Technology and Industrial Pharmacy. Nigeria: Samakin (Nig) Enterprise.

·        Shayne, C.