Signals that come from outside a cell (extracellular signals) may be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas). Cell signalling can occur over short or long distances. Signalling molecules can be released through passive or active transports, or even from cell damage.
Receptors play a key role in cell signaling as they are able to detect chemical signals or physical stimuli. Receptors are generally proteins on the cell surface or in the interior of the cell. Examples are the cytoplasm, organelles, and nucleus.
References[change | change source]
- Neitzel, James; Rasband, Matthew. "Cell communication". Nature Education. Retrieved 29 May 2021.
- "Cell signaling". Nature Education. Retrieved 29 May 2021.
- Vu TQ, de Castro RM, Qin L (14 March 2017). "Bridging the gap: microfluidic devices for short and long distance cell-cell communication". Lab on a Chip. 17 (6): 1009–1023. doi:10.1039/c6lc01367h. PMC 5473339. PMID 28205652.
- Lodish, Harvey; Berk, Arnold.; Kaiser, Chris A.; Krieger, Monty; Scott, Matthew P.; Bretscher, Anthony; Ploegh, Hidde; Matsudaira, Paul (2008). "Cell signaling I: Signal transduction and short-term cellular processes". Molecular Cell Biology (6th ed.). New York: W.H. Freeman and Company. pp. 623–664. ISBN 978-0716776017.