Fred McLafferty

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Fred W. McLafferty
Born (1923-05-11) May 11, 1923 (age 96)
ResidenceUnited States
NationalityUnited States
Alma materUniversity of Nebraska
Cornell University
Known forMass Spectrometry
AwardsACS Award in Chemical Instrumentation (1972 )

Fisher Award (1981)

Member of the National Academy of Sciences (1982 )
ACS Nichols Gold Medal (1984 )
Oesper Award (1985 )
Sir J.J. Thomson Gold Medal (1985 )
Field and Franklin Award (1989)
ASMS Distinguished Contribution in Mass Spectrometry Award (2003)
Lavoisier Medal (2004)[1]
Scientific career
FieldsChemist
InstitutionsPurdue University
Cornell University
Doctoral studentsI. Jonathan Amster


Fred Warren McLafferty is an American chemist known for his work in mass spectrometry. He is best known for the McLafferty rearrangement reaction that was observed with mass spectrometry.[2] With Roland Gohlke, he pioneered the technique of gas chromatography–mass spectrometry.[3] He is also known for electron capture dissociation, a method of fragmenting gas phase ions.[4]

References[change | change source]

  1. "Seven Cornellians receive prestigious national and international honors". Cornell Chronicle. December 3, 2004. Retrieved 2014-08-28.
  2. F. W. McLafferty (1959). "Mass Spectrometric Analysis. Molecular Rearrangements". Analytical Chemistry 31 (1): 82–87. doi:10.1021/ac60145a015. 
  3. Gohlke, Roland S.; McLafferty, Fred W. (1993). "Early gas chromatography/mass spectrometry". Journal of the American Society for Mass Spectrometry 4 (5): 367–371. doi:10.1016/1044-0305(93)85001-E. 
  4. Zubarev, R. A.; Kelleher, N. L.; McLafferty, F. W. (1998). "Electron Capture Dissociation of Multiply Charged Protein Cations - a Nonergodic Process". J. Am. Chem. Soc. 120 (13): 3265–3266. doi:10.1021/ja973478k.