Jones won an Academy Award and a Golden Globe Award for her role as Bernadette Soubirous in The Song of Bernadette. She was also nominated for Academy Awards for her roles in: Since You Went Away, Love Letters, Duel in the Sun and Love Is a Many-Splendored Thing.
Jones married actor Robert Walker (1918-1951) in 1939. They had two sons, actor Robert Walker, Jr. (born 1940) and Michael Walker (1941-2007). The couple divorced in 1945. She was married to movie producer David O. Selznick (1902-1965) from 1949 until his death. The couple had a daughter, Mary Jennifer Selznick (1954-1976). Jones was married to businessman Norton Simon (1907-1993) from 1971 until his death.
She died in Malibu, California.