List of fentanyl analogues
This is a list of some fentanyl analogues (Fentalogs).[1][2][3]
The list has [famous] chemical compounds from (drug companies or) pharmaceutical companies for legitimate medical use. The list also has compounds that have been sold as designer drugs and reported to drug control agencies such as the DEA, or EMCDDA and UNODC.[4][5][6][7][8][9][10]
List[change | change source]
| Chemical structure | Common name | More information | |
|---|---|---|---|
|
2,5-Dimethylfentanyl | ||
|
2,2'-Difluorofentanyl | ||
|
3-Allylfentanyl | ||
|
3-Fluorofentanyl (NFEPP) | ||
|
3-Methylbutyrfentanyl |
| |
|
3-Methylfentanyl (3-MF) | ||
|
3-Methylthiofentanyl | ||
|
3-Phenylpropanoylfentanyl[11] | ||
|
4-Fluorobutyrfentanyl (4-FBF) | ||
|
4-Chloroisobutyrylfentanyl (4-CIBF) [12] | ||
|
4-Fluoroisobutyrfentanyl (4-FIBF) | ||
|
4-Fluorofentanyl | ||
|
para-fluorofuranylfentanyl[13] (p-F-Fu-F) | ||
|
4-Phenylfentanyl | ||
|
4-Methoxybutyrfentanyl | ||
|
4-Methylphenethylacetylfentanyl[14] | ||
|
Acrylfentanyl | ||
|
α-Methylacetylfentanyl | ||
|
AMF, or α-Methylfentanyl | ||
|
α-Methylthiofentanyl | ||
|
Acetylfentanyl | ||
|
Alfentanyl | ||
|
Benzodioxolefentanyl[15] |
References[change | change source]
- ↑ Hassanien SH, Bassman JR, Perrien Naccarato CM, Twarozynski JJ, Traynor JR, Iula DM, Anand JP (August 2020). "In vitro pharmacology of fentanyl analogs at the human mu opioid receptor and their spectroscopic analysis". Drug Testing and Analysis. 12 (8): 1212–1221. doi:10.1002/dta.2822. PMC 8034271. PMID 32415719.
- ↑ Vaughan SR, Fulton AC, DeGreeff LE. Comparative analysis of vapor profiles of fentalogs and illicit fentanyl. Anal Bioanal Chem 413, 7055–7062 (2021). doi:10.1007/s00216-021-03670-4
- ↑ Patel JC, Parveen S (January 2022). "In Vitro and In Vivo Analysis of Fentanyl and Fentalog Metabolites using Hyphenated Chromatographic Techniques: A Review". Chemical Research in Toxicology. 35 (1): 30–42. doi:10.1021/acs.chemrestox.1c00225. PMID 34957817. S2CID 245500557.
- ↑ Mounteney J, Giraudon I, Denissov G, Griffiths P (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe". The International Journal on Drug Policy. 26 (7): 626–31. doi:10.1016/j.drugpo.2015.04.003. PMID 25976511.
- ↑ Zawilska JB (2017). "An Expanding World of Novel Psychoactive Substances: Opioids". Frontiers in Psychiatry. 8: 110. doi:10.3389/fpsyt.2017.00110. PMC 5492455. PMID 28713291.
- ↑ "Recommended Methods for the Identification and Analysis of Fentanyl and its Analogues in Biological Specimens" (PDF). United Nations Office on Drugs and Crime. November 2017.
- ↑ Vardanyan RS, Hruby VJ (March 2014). "Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications". Future Medicinal Chemistry. 6 (4): 385–412. doi:10.4155/fmc.13.215. PMC 4137794. PMID 24635521.
- ↑ Armenian P, Vo KT, Barr-Walker J, Lynch KL (May 2018). "Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review". Neuropharmacology. 134 (Pt A): 121–132. doi:10.1016/j.neuropharm.2017.10.016. PMID 29042317. S2CID 21404877.
- ↑ Fentanyl-related substances with no known legitimate uses. International Narcotics Control Board, 24 June 2018
- ↑ Choińska MK, Šestáková I, Hrdlička V, Skopalová J, Langmaier J, Maier V, Navrátil T (January 2022). "Electroanalysis of Fentanyl and Its New Analogs: A Review". Biosensors. 12 (1). doi:10.3390/bios12010026. PMC 8774265. PMID 35049654.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ↑ Rautio T, Vangerven D, Dahlén J, Watanabe S, Kronstrand R, Vikingsson S, et al. (February 2023). "In vitro metabolite identification of acetylbenzylfentanyl, benzoylbenzylfentanyl, 3-fluoro-methoxyacetylfentanyl, and 3-phenylpropanoylfentanyl using LC-QTOF-HRMS together with synthesized references". Drug Testing and Analysis. doi:10.1002/dta.3454. PMID 36756728.
- ↑ Le AD, Alzghari SK (October 2019). "Systematic review of the clinical consequences of butyrfentanyl and corresponding analogues". Interdisciplinary Toxicology. 12 (2): 83–88. doi:10.2478/intox-2019-0009. PMC 7071838. PMID 32206028.
- ↑ Vincenti F, Montesano C, Di Ottavio F, Gregori A, Compagnone D, Sergi M, Dorrestein P (2020). "Molecular Networking: A Useful Tool for the Identification of New Psychoactive Substances in Seizures by LC-HRMS". Frontiers in Chemistry. 8: 572952. doi:10.3389/fchem.2020.572952. PMC 7723841. PMID 33324608.
- ↑ Moore JM, Allen AC, Cooper DA, Carr SM (July 1986). "Determination of fentanyl and related compounds by capillary gas chromatography with electron capture detection". Analytical Chemistry. 58 (8): 1656–60. doi:10.1021/ac00121a013. PMID 3752503.
- ↑ Varshneya NB, Walentiny DM, Moisa LT, Walker TD, Akinfiresoye LR, Beardsley PM (June 2019). "Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances". Neuropharmacology. 151: 171–179. doi:10.1016/j.neuropharm.2019.03.023. PMC 8992608. PMID 30904478. S2CID 84182661.
