Puromycin

From Simple English Wikipedia, the free encyclopedia

Puromycin is an antibiotic protein synthesis inhibitor.

It causes premature chain termination during translation in the ribosome. Puromycin is used in cell biology as a selective agent in cell culture systems. It is toxic to prokaryotic and eukaryotic cells.

Puromycin is an example of a eukaryotic selection compound. These are compounds which are used in biological research to select for cells/organisms that carry the appropriate resistance gene for the compound.