From Wikipedia, the free encyclopedia
Jump to: navigation, search
Systematic (IUPAC) name
CAS number 139755-83-2
ATC code G04BE03
PubChem 5281023
DrugBank DB00203
ChemSpider 56586
Chemical data
Formula C22H30N6O4S 
Mol. mass base: 474.6 g/mol
Pharmacokinetic data
Bioavailability 40%
Metabolism Hepatic (mostly CYP3A4, also CYP2C9)
Half life 3 to 4 hours
Excretion Fecal (80%) and renal (around 13%)
Therapeutic considerations
Licence data

EU EMEA:linkUS FDA:link

Pregnancy cat.


Legal status

Rx-only Template:Where?

Routes Oral, IV

Sildenafil is a medication that is also called Viagra, Revatio and (in the Indian subcontinent) Caverta.

Sildenafil makes the blood vessels become wider. This lowers the blood pressure. Sildenafil mostly works in the penis and in the lungs. This medicine increases blood flow to the penis. This helps the penis become erect during sexual intercourse.[1] Sildenafil also helps pulmonary hypertension. Because this medicine makes the blood vessels wider, it makes it easier for blood to flow. Sildenafil was patented in 1996 and first made to sell in 1998.

Related pages[change | change source]

References[change | change source]

  1. eMedicine. "Erectile Dysfunction - Treatment". Retrieved 26 February 2010.