The Cornish Rebellion of 1497 started in St Keverne. The leader of the rebellion Michael An Gof was a blacksmith from St Keverne and is commemorated by a statue in the village.
The parish is a large one and includes some 10 miles of coast from Nare Point at the mouth of the Helford River to Kennack Sands, and the Manacles offshore. Settlements on the coast include Porthallow, Porthoustock and Coverack. Inland the parish includes the hamlets of Zoar, Laddenvean, Traboe, Trelan and Gwenter. The eastern part of Goonhilly Downs is also in the parish.
St Keverne was in the Middle Ages the site of an important monastery. The church is dedicated to St Akeveranus. The church is very large for a village church and in its present form is 15th century.