From Simple English Wikipedia, the free encyclopedia

Statin drugs, also known as HMG-CoA reductase inhibitors, are lipid-lowering drugs that reduce illness in people who have a high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs.[1]

Low-density lipoprotein (LDL) carriers of cholesterol play key roles in arteriosclerosis, stroke and coronary heart disease.[2]

The common side effects of statins are diabetes mellitus, nausea, hormonal imbalance, and muscle pains.[3][4]

Atorvastatin, one of the most commonly prescribed brands, was in short supply in England in 2023 and the price rose from 49p through to £5.30 per pack. [5]

References[change | change source]

  1. "Cholesterol Drugs". American Heart Association. Retrieved May 24, 2021.
  2. National Clinical Guideline Centre (UK) (2014). "Lipid Modification". National Institutes of Health. PMID 25340243. Retrieved May 24, 2021. {{cite journal}}: Cite journal requires |journal= (help)
  3. "Comparative Tolerability/Harms of Individual Statins" (PDF). London School of Economics. Retrieved May 24, 2021. {{cite journal}}: Cite journal requires |journal= (help)
  4. Schooling, C. Mary; Au Yeung, Shiu Lun; Freeman, Guy; Cowling, Benjamin J. (2013-02-28). "The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials". BMC Medicine. 11 (1): 57. doi:10.1186/1741-7015-11-57. ISSN 1741-7015. PMC 3621815. PMID 23448151.
  5. "Negotiators warn statin shortage is having 'serious impact' on pharmacies as price spikes". The Pharmaceutical Journal. 2023-07-06. Retrieved 2023-07-07.