Chimaera (genetics)

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A chimeric mouse with its offspring

A chimaera or chimera is a single organism (usually an animal) made of two kinds of genetically distinct cells. The two types of cells came from separate fertilised eggs or zygotes.[1]

If the different cells have come from the same zygote, the organism is called a mosaic. Chimaeras are formed from at least two fertilized eggs or early embryos fused together. Each population of cells keeps its own character and the resulting organism is a mixture of tissues. Chimaeras are typically seen in animals.

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  1. King R.C; Stansfield W.D. & Mulligan P.K. 2006. A dictionary of genetics. Oxford University Press, p73. ISBN 0-19-530761-5