Pulmonary hypertension or PH is a disease where there is high blood pressure in the lungs. The disease makes it hard to breathe. Some people with the disease need extra oxygen. This disease can also make a person dizzy and become easily tired. Some people with the disease faint easily. The symptoms get worse when exercising or working hard. Pulmonary hypertension is a serious disease, and it can be fatal. The disease makes it harder for the heart to pump blood. Because the heart has to work harder, it can also become sick. Some people who are very sick may need a lung transplant or a heart-lung transplant to live.
Signs and symptoms [change]
People with pulmonary hypertension have difficulty breathing. They also tire easily. Some of them faint easily too. They might have chest pain. Some patients have swelling of the feet and ankles. These symptoms get worse during exercise or hard work.
Because many diseases can make it hard to breathe, a doctor must learn about the patient's background. This helps the doctor to treat the patient, even if the patient has another disease. The doctor also does several tests. Pulmonary hypertension makes the heart sound different. One test is to measure the blood pressure inside the pulmonary artery, the blood vessel that goes from the heart to the lungs.
What goes wrong with the body [change]
In pulmonary hypertension, the blood vessels in the lungs become too narrow. The blood pressure in the lungs becomes high. The heart works very hard to pump blood through the narrow blood vessels. Later on, the blood vessels in the lungs become hard and thick. The heart must work harder.
The heart can work so hard that it becomes sick. This is called heart failure. The sick heart cannot pump blood well. Less blood goes to the lungs, so the blood gets less oxygen. This makes it hard to breathe. This gets worse when exercising or working hard.
Many illnesses can cause pulmonary arterial hypertension (PAH).
- Lung diseases that make the blood have less oxygen, such as:
- immune system problems, such as:
- liver problems
- other causes
When a person has pulmonary hypertension without any other cause, this is called idiopathic pulmonary arterial hypertension or IPAH.
When a family history exists, the disease is termed familial pulmonary arterial hypertension, (FPAH). IPAH and FPAH are now considered to be genetic disorders linked to mutations in the BMPR2 gene, which encodes a receptor for bone morphogenetic proteins, as well as the 5-HT(2B) gene, which codes for a serotonin receptor.
Other websites [change]
- The Merck Manual of Diagnosis and Therapy: Pulmonary Hypertension
- PH Central - the internet resource for Pulmonary Arterial Hypertension
- The Pulmonary Hypertension Association Webpage provided by the Pulmonary Hypertension Association
- Facts About Primary Pulmonary Hypertension from the National Heart, Lung, and Blood Institute (NHLBI)
- Webcast: The Changing World of Pulmonary Arterial Hypertension Therapies - American College of CHEST Physicians
- Pulmonary Arterial Hypertension Information for Healthcare professionals
- BMPR2-Related Primary Pulmonary Hypertension on GeneReviews
- "Pharmacies for Cialis (Generic Name: Tadalafil)". http://onlinepharmacy.myegates.com/iresults.php?qq=buy+cialis.
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