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George Church

From Simple English Wikipedia, the free encyclopedia
George Church
Church with a molecular model at TED 2010
Born (1954-08-28) August 28, 1954 (age 69)
MacDill Air Force Base, Florida
Alma materDuke, Harvard
Known forDNA sequencing
Scientific career
InstitutionsHarvard, MIT

George Church (born August 28, 1954) is an American molecular geneticist. He was one of the people who set out to analyse the human genetic code, the sequence of genes in human DNA.[1]

Church is Professor of Genetics at Harvard Medical School,[2] Professor of Health Sciences and Technology at Harvard and MIT,[3] and a core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University.[4][5][6]

With Walter Gilbert he developed the first direct genomic sequencing method in 1984,[7] and helped start the Human Genome Project while he was a research scientist at newly formed Biogen Inc.[8]

He invented ways of analysing huge amounts of chemical data,[9] homologous recombination methods,[10] and DNA array synthesizers. Automated sequencing & software in Genome Therapeutics Corp. gave the first commercial genome sequence, (the human pathogen, Helicobacter pylori) in 1994.[11]

Church started the Personal Genome Project (PGP) in 2005,[12] and in 2007 he founded the U.S. personal genomics company Knome (with Jorge Conde and Sundar Subramaniam).[13]

Church does research on synthetic (artificial) biology and is director of the U.S. Department of Energy Center on Bioenergy at Harvard & MIT,[14] and Director of the National Institutes of Health Center of Excellence in Genomic Science at Harvard.[15]

He has been advisor to 22 companies.[16] He co-founded Codon Devices, a biotech startup dedicated to synthetic biology. It produces DNA sequences to order.[17] He co-founded LS9, which is focused on biofuels or renewable petroleum technologies.[18]

In 2009 he founded Pathogenica, with Yemi Adesokan, in order to pioneer commercial applications for pathogen sequencing technology.[19]

In September 2010, Dr. Church was honored for his work in genetics with the Mass High Tech All-Star Award.[20] He is a senior editor for Molecular Systems Biology.[21]

According to Forbes, Church suffers from narcolepsy.

References[change | change source]

  1. Weintraub, Karen 2011. Will we all be tweaking our own genetic code? BBC News: Technology [1]
  2. Harvard Medical School Department of Genetics HMS Genetics Faculty
  3. Harvard-MIT Health Sciences and Technology HST Archived 2011-09-27 at the Wayback Machine
  4. "Wyss Institute Core Faculty". Archived from the original on 2011-09-16. Retrieved 2011-09-19.
  5. "Harvard Molecular Technology Group & Lipper Center for Computational Genetics". Retrieved 2011-07-05.
  6. "George M. Church: personal history & interests (unauthorized autobiography & infrequently asked questions)". Retrieved 2011-07-05.
  7. Church G. & Gilbert W. 1984. Genomic sequencing. Proceedings of the National Academy of Sciences of the United States of America 81 (7): 1991–1995. [2] PMID 6326095
  8. Cook-Deegan R.M. 1989. The Alta summit, December 1984. Genomics 5 (3): 661–663. PMID 2613249
  9. Church G. & Kieffer-Higgins S. 1988. Multiplex DNA sequencing. Science 240 (4849): 185–188. PMID 3353714
  10. Link A.J.; Phillips D. and Church G.M. 1997. Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: Application to open reading frame characterization. Journal of bacteriology 179 (20): 6228–6237. PMID 9335267
  11. Editorial: Capitalizing on the genome. Nature Genetics 13 (1): 1–5. 1996. [3] PMID 8673083
  12. Church G.M. 2005. The Personal Genome Project. Molecular Systems Biology 1: E1–E3. [4] PMID 16729065
  13. Dickinson, Boonsri (2010-06-10). "Geneticist George Church: Sequencing human genome 'high priority' for China". Smart Planet. Archived from the original on 2010-08-14. Retrieved 2010-08-18.
  14. DOE Genomes to Life Center
  15. Centers of Excellence in Genomic Science Awards
  16. Duncan, David (2010-06-07). "Scientist at work: George M. Church - On a mission to sequence the genomes of 100,000 People". The New York Times. Retrieved 2010-08-18.
  17. Herper M (2006). "Photoshop For DNA". Forbes.[5] Archived 2008-10-24 at the Wayback Machine
  18. San Francisco Business Times - March 12, 2007
  19. "Pathogenica Bets on Next-Gen Sequencing for Fast, Multiplexed Pathogen Detection". GenomeWeb. 2010-07-06. Retrieved 2011-09-06.
  20. "All-Star Awards". Mass High Tech. 2010-09-08. Archived from the original on 2010-09-02. Retrieved 2010-09-08.
  21. "About the editors: Molecular Systems Biology". Retrieved 2011-07-05.

Other websites[change | change source]