She is best known for playing Eileen Grimshaw in the long-running ITV soap opera Coronation Street, a role she has played continuously since May 2000. She also played Glenda alongside Victoria Wood in the BBC One sitcom Dinnerladies from 1998 to 2000. She was covering for Denise Robertson as the agony aunt on ITV daytime programme This Morning until Robertson's death in 2016. She is currently participating on the ITV celebrity show I'm a Celebrity...Get Me Out of Here!. Cleaver was born in Watford, Hertfordshire, England and moved to Manchester as a teenager.
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