U.S. Route 425

U.S. Route 425
Major junctions
From	US 61 / US 84 at Natchez, MS
Major intersections	I-20 at Rayville, LA
To	I-530 / US 63 / US 65 / US 79 at Pine Bluff, AR
Location
Country	United States
Highway system
United States Numbered Highway System List Special Divided

U.S. Route 425 (US 425) is a north–south United States highway in the U.S. states of Mississippi, Louisiana, and Arkansas. Its north end is Pine Bluff, Arkansas, and its south end is Natchez, Mississippi.