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This editor has NOT been awarded the Society Barnstar   but does live in one!!

Troponin is released into the bloodstream


[change | change source]

Warfarin[change | change source]

Pregnancy is a known hypercoaguable state [1]

Poisoning by ingestion, inhalation or absorption through the skin of BDF shows no signs or symptoms in humans other than delayed (after several days) development of severe, long-lasting (up to months) bleeding events. Consequently, victims may not suspect nor report exposure to BDF before overt bleeding is observed. Once manifested, bleeding is prolonged and can be fatal at high doses due to the long biological half-life of BDF which has been estimated to be over 90 days in serum, and almost 10 months in liver (Vandenbroucke et al., 2008), one of its main storage sites and where levels can reach 50-fold or greater than that in other tissues (Hauck et al., 2016). Importantly, BDF poisoning can be fatal if left untreated even at relatively small amounts (∼15 mg).[2]

Currently, although there exist means to attenuate the consequences of superwarfrain induced anti-coagulation, there are no FDA-approved drugs to eliminate BDF from tissues. Hence, various blood products and vitamin K1, an FDA-approved drug that increases vitamin K levels allowing activation of coagulation factors and provides anticoagulant effects throughout the body, are provided to patients until BDF no longer interferes with coagulation, a period which can extend for months, after which symptoms may reappear (Card et al., 2014, Underwood et al., 2014). However, since these treatments do not inactivate or eliminate BDF from the body, the long half-life (months) of BDF necessitates extended (months) courses of high-dose (up to 600 mg/day, 120 tablets) vitamin K supplementation which is very expensive (hundreds of US dollars per month) resulting in poor adherence by the patients.[2]

KETAMINE[change | change source]

Doubt onset | Ketamine = bone fractures, analgesia, horses | Wikipedia = [13], sinner B; ...

Clinical data
Trade namesKetalar ...
License data
Routes of
Drug classNMDA receptor antagonists; General anesthetics; Dissociative hallucinogens; Analgesics; Antidepressants
Pharmacokinetic data
MetabolismLiver, intestine (oral):[8][10][11]
Elimination half-life
  • Ketamine: 2.5–3 hours[15][8]
  • Norketamine: 12 hours[16]
Duration of action
  • Intramuscular: 0.5–2 hours[16]
  • Insufflation: 45–60 min[15]
  • By mouth: 1–6+ hours[15][16]
  • (RS)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
Chemical and physical data
Molar mass237.73 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture:[15]
Melting point92[18] °C (198 °F)
  • Clc1ccccc1C2(NC)CCCCC2=O
  • InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3 checkY


Fundus photograph of the left eye, showing a fundus with no sign of disease or pathology. It is seen from front so that left in each image is to the person's right. The gaze is into the camera, so the macula is in the center of the image, and the optic disk is located towards the nose (left in image). The optic disk has some pigmentation at the perimeter of the lateral side, which is considered non-pathological.}}.


Licensing[change | change source]

I, the copyright holder of this work, hereby publish it under the following license:

HEART[change | change source]

I haven't gotten to thr heart yet, but https://simple.m.wikipedia.org/wiki/Oedema Mostly in thr legs when it is the heart, because of a specific chamber not working (i think it is the right side), but one side will cause other symptoms instead. It is a circulation issue. (TODO)

PREGNANCY[change | change source]

(Actually period pain (dysmenorrhoea)) References ↑

McKenna KA, Fogleman CD (August 2021). "Dysmenorrhea". Am Fam Physician. 104 (2): 164–170. PMID 34383437. American College of Obstetricians and Gynecologists (Jan 2015). "FAQ046 Dynsmenorrhea: Painful Periods" (PDF). Archived (PDF) from the original on 27 June 2015. Retrieved 26 June 2015.

deleted information[change | change source]

rollback / edit war[change | change source]


Check out https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
At one point the article the editor had the cause of death ranking wrong (and uses future predictions insread of past information). This is cited
Those are terrible bulletpoints which could be shortened down a lot. One of the bullet points I edited is the issue, which saw the whole article rolled back.
The "jargon" is used in brackets () with links to other wikipedia pages. This article rollback put information back in the article about the circulation which is wrong. W;ChangingUsername (talk) 18:03, 22 May 2024 (UTC)
Respectfully we're not a medical website, Anywho go to WP:Simple talk as others may disagree with me or may agree and either way will be able to help you better than I can, Thanks, –Davey2010Talk 18:07, 22 May 2024 (UTC)
Added. https://simple.m.wikipedia.org/wiki/Wikipedia:Simple_talk#Stroke_page in case you want to take part in the discussion.
And (reapectfully) the rules say the article needs to be written simply, not that it needs to be less detailed or cover information worse. Roll back your article properly if youre going to try and make it entirely your own

And the FAST memory aid should be remembered by everyone to help spot strokes. W;ChangingUsername (talk) 18:19, 22 May 2024 (UTC)

Never once said it needs to be less detailed or cover worse information, I'm simply saying your edits aren't an improvement over what is there. Thanks. –Davey2010Talk 18:23, 22 May 2024 (UTC)

Rockefeller family[change | change source]

Tens of thousands of characters deleted (changes page revision link)

  1. "Anticoagulation During Pregnancy: Evolving Strategies". American College of Cardiology. Retrieved 2024-06-02.
  2. 2.0 2.1 https://www.sciencedirect.com/science/article/abs/pii/S0378427417300048#:~:text=Poisoning%20by%20ingestion%2C%20inhalation%20or,before%20overt%20bleeding%20is%20observed. {{cite web}}: Missing or empty |title= (help)
  3. "Drug Scheduling". US DEA. Archived from the original on 8 April 2024. Retrieved 29 December 2023. {{cite web}}: line feed character in |title= at position 5 (help) Ketamine is listed in Schedule III.
  4. Huang, MC., Lin, SK. (2020). Ketamine Abuse: Past and Present. In: Hashimoto, K., Ide, S., Ikeda, K. (eds) Ketamine. Springer, Singapore. https://doi.org/10.1007/978-981-15-2902-3_1
  5. "Ketamine (Ketalar) Use During Pregnancy". Drugs.com. 22 November 2019. Archived from the original on 26 June 2020. Retrieved 18 May 2020.
  6. Bell RF, Eccleston C, Kalso EA (June 2017). "Ketamine as an adjuvant to opioids for cancer pain" (PDF). The Cochrane Database of Systematic Reviews. 6 (9): CD003351. doi:10.1002/14651858.CD003351.pub3. PMC 6481583. PMID 28657160. Archived (PDF) from the original on 12 January 2024. Retrieved 10 September 2018.
  7. Moyse DW, Kaye AD, Diaz JH, Qadri MY, Lindsay D, Pyati S (March 2017). "Perioperative Ketamine Administration for Thoracotomy Pain". Pain Physician. 20 (3): 173–184. PMID 28339431.
  8. 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Mathew SJ, Zarate Jr CA (25 November 2016). Ketamine for Treatment-Resistant Depression: The First Decade of Progress. Springer. pp. 8–10, 14–22. ISBN 978-3-319-42925-0. Archived from the original on 8 September 2017.
  9. Brayfield A, ed. (9 January 2017). "Ketamine Hydrochloride: Martindale: The Complete Drug Reference". MedicinesComplete. London, UK: Pharmaceutical Press. Archived from the original on 28 August 2021. Retrieved 24 August 2017.
  10. Hijazi Y, Boulieu R (July 2002). "Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes". Drug Metabolism and Disposition. 30 (7): 853–8. doi:10.1124/dmd.30.7.853. PMID 12065445. S2CID 15787750.
  11. Cite error: The named reference pmid27763887 was used but no text was provided for refs named (see the help page).
  12. Kintz P (22 March 2014). Toxicological Aspects of Drug-Facilitated Crimes. Elsevier Science. pp. 87–. ISBN 978-0-12-416969-2. Archived from the original on 8 September 2017.
  13. Marland S, Ellerton J, Andolfatto G, Strapazzon G, Thomassen O, Brandner B, Weatherall A, Paal P (June 2013). "Ketamine: use in anesthesia". CNS Neurosci Ther. 19 (6): 381–9. doi:10.1111/cns.12072. PMC 6493613. PMID 23521979.
  14. Hashimoto K (October 2019). "Rapid-acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective". Psychiatry and Clinical Neurosciences. 73 (10): 613–627. doi:10.1111/pcn.12902. PMC 6851782. PMID 31215725.
  15. 15.0 15.1 15.2 15.3 Cite error: The named reference sinner was used but no text was provided for refs named (see the help page).
  16. 16.0 16.1 16.2 Cite error: The named reference Quibell2011 was used but no text was provided for refs named (see the help page).
  17. 17.0 17.1 Cite error: The named reference pmid4603048 was used but no text was provided for refs named (see the help page).
  18. Sass W, Fusari S (1977). "Ketamine". Analytical Profiles of Drug Substances. Vol. 6. Academic Press. pp. 297–322. doi:10.1016/S0099-5428(08)60347-0. ISBN 9780122608063.