Types of agonists[change | change source]
Receptors can be activated by either endogenous or exogenous agonists. Both types result in a biological response. Endogenous agonists include hormones and neurotransmitters. Exogenous agonists include drugs.
A substance which causes the same bodily responses, but does not bind to the same receptor is called a physiological agonist.
Examples[change | change source]
- The endogenous agonist for serotonin receptors is serotonin, and the endogenous agonist for dopamine receptors is dopamine.
- Morphine is an exogenous agonist. It mimics the actions of endorphins at certain receptors in the central nervous system.
References[change | change source]
- Goodman and Gilman's Manual of Pharmacology and Therapeutics. (11th edition, 2008). p14. ISBN 0-07-144343-6
- they are called μ-opioid receptors