It is on the site of the old Lehrter Bahnhof. Until it opened as a main line station, it was a stop on the Berlin S-Bahn suburban railway, temporarily named Berlin Hauptbahnhof - Lehrter Bahnhof in 2002.
The longest route that runs through Berlin Hauptbanhof is the Sibirjak. It links Berlin to some cities in Russia. It passes through Poland, Belarus, Russia and Kazakhstan. The longest route offered goes to Novosibirsk. This takes almost four days to travel.