Culebra (meaning snake in Spanish) has several meanings:
- Island of Culebra, part of Puerto Rico.
- Culebra Peak, the southernmost fourteener in Colorado, USA.
- Culebra (automobile), an English automobile manufactured in 1989.
- The Culebra Cut, an artificial valley located in the Panama Canal area, was renamed the Gaillard Cut in 1915.
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