Coordinates: 6°45′N 57°59′W / 6.750°N 57.983°W / 6.750; -57.983
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Map of Guyana showing Demerara-Mahaica region

Demerara-Mahaica (Region 4) is a region in the north of Guyana. The regional capital is Georgetown, which is also the national capital.

The region has an area of 2,232 km². As of the 2012 census, 313,429 people lived there. It borders the Atlantic Ocean to the north, the region of Mahaica-Berbice to the east, the region of Upper Demerara-Berbice to the south and the region of Essequibo Islands-West Demerara to the west.

6°45′N 57°59′W / 6.750°N 57.983°W / 6.750; -57.983