Emanuele Macaluso (21 March 1924 – 19 January 2021) was an Italian trade unionist, journalist and politician. He was born in Caltanissetta, Italy. He was an editor of L'Unità.
Macaluso was a member of the Italian Communist Party. From 1963 to 1976, he was a member of the Chamber of Deputies. From 1976 to 1992, Macaluso was a member of the Senate.
Macaluso died on 19 January 2021 in Rome from problems caused by a fall, aged 96.