The human microbiome (or human microbiota) is the collection of microorganisms which live on us. They live on the skin, in the saliva and mouth, in the eyes, and in the gut and the rest of the gastrointestinal tract. They include bacteria, archaea, fungi and single-celled eukaryotes ('protozoa'). Everyone carries around far more of these microbes than the number of human cells in the body. The human body has about 100 trillion cells, and carries about ten times as many microorganisms in the intestines alone.
Some of these organisms are useful for humans. However, most have no known effect. They are just symbionts: they live with us. Those which are expected to be present are members of the normal flora. Under normal circumstances they do not cause disease, but may even help our health. Studies in 2009 asked whether our health is damaged if we reduce this biota. This is certainly the case with gut flora.
Although "flora" refers to plants rather than bacteria, the term 'gut flora' is widely used and familiar to biologists. 'Biota' refers to the total collection of organisms in an ecosystem. The term 'microbiota' is best for bacteria and other microorganisms, but no doubt 'flora' will often be used.
References[change | edit source]
- Mundasad, Smitha 2012. Human Microbiome Project reveals largest microbial map. BBC News: Health 
- Björkstén B, Sepp E, Julge K, Voor T, Mikelsaar M (October 2001). "Allergy development and the intestinal microflora during the first year of life". J. Allergy Clin. Immunol. 108 (4): 516–20. doi:10.1067/mai.2001.118130. PMID 11590374.
- Guarner F, Malagelada JR (2003). "Gut flora in health and disease". Lancet 361 (9356): 512–9. doi:10.1016/S0140-6736(03)12489-0. PMID 12583961.
- Sears CL (October 2005). "A dynamic partnership: celebrating our gut flora". Anaerobe 11 (5): 247–51. doi:10.1016/j.anaerobe.2005.05.001. PMID 16701579.
- Steinhoff U (June 2005). "Who controls the crowd? New findings and old questions about the intestinal microflora". Immunol. Lett. 99 (1): 12–6. doi:10.1016/j.imlet.2004.12.013. PMID 15894105.
- Bugs inside: what happens when the microbes that keep us healthy disappear?, Katherine Harmon, Scientific American, December 2009, accessed 27 December 2009