Talk:Paracetamol

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

Explaining my edit[change source]

I think the difference here may be American vs. other types of English. Here in the US, "go to the hospital" is exclusively used whether one is visiting or admitted, and it may be different elsewhere. Kansan (talk) 18:48, 18 January 2011 (UTC)

I know that this may be British usage, and as I am not a native speaker, I was probably wrong to correct it. Can we perhaps settle for a statement "mid-way" (that avoids this discussion over a preposition?) --Eptalon (talk) 18:51, 18 January 2011 (UTC)

Knowledge of dosage[change source]

The text twice says ignorance of dosage is a major cause of acute liver failure. I do not believe this, and reading refs such as #1 find that 'accidental overdose' is used, not ignorance of dosage. I think (personal opinion) no drug has had its dosage more advertised than paracetamol. I think the legal restrictions on codeine-based preparations (now rated as Class 3 drugs) has led to many people overusing paracetamol.

Anyway, my point is that the refs do not seem to support the wording as is. Macdonald-ross (talk) 08:52, 19 January 2011 (UTC)

Ref 1 (Larson, et al.) talks about "unintentional overdose", which accounted for 131 of 275 cases (48%), 122 (44%) were suicide attempts, in the remaining 22 cases (8%), clear attribution was not possible. The median dose ingested (for the "unintentional" group) was 20g. One of the problems I see is that there are medications that combine Paracetamol with other substances (eg. a narcotic,such as hydrocodone - a synthetic opiate; "Vicodin") (63% of the unintentional group); 38% of the group used two drugs containing Paracetamol. - The problem (my opinion) may not be "labeling the package", but "recognising the Paracetamol", and being able to accurately add the doses. --Eptalon (talk) 10:15, 19 January 2011 (UTC)
Yes, 'unintentional overdose' is not necessarily ignorance of dosage. I agree that recognising the paracetamol probably comes into it, though that also is an interpretation. Macdonald-ross (talk) 10:39, 19 January 2011 (UTC)
So what is the wording we should use to mirror unintentional overdose? --Eptalon (talk) 10:43, 19 January 2011 (UTC) -question moot, you already changed it; thanks. --Eptalon (talk) 10:46, 19 January 2011 (UTC)

(It is still hard to believe; the "common" Paracetamol dosage here (for OTC) is max. 250 mg (or thereabouts). - 10 Tablets -> 2.5g, 20g would therefore be around 80 tablets, "taken accidentally"...) --Eptalon (talk) 21:15, 19 January 2011 (UTC)