User:Doc James/Temp Translation
Doc James/Temp Translation | |
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Other names | Legg–Calvé–Perthes syndrome, Perthes disease, Legg–Perthes disease, Calves disease |
Radiograph of a person with Legg–Calvé–Perthes disease | |
Pronunciation | |
Specialty | Orthopedics |
Symptoms | Limp, hip pain[1] |
Complications | Osteoarthritis[1] |
Usual onset | 4 to 8 years[1] |
Risk factors | Genetics, blood clotting problems, exposure to cigarette smoke, extreme motion at the hip[1] |
Diagnostic method | X-rays[1] |
Differential diagnosis | Sickle cell disease, lupus, chemotherapy, long-term corticosteroid use, multiple epiphyseal dysplasia[1] |
Treatment | NSAIDs, decreasing physical activity, physical therapy, surgery[1] |
Prognosis | Usually good[2] |
Frequency | 1 in 1200[3] |
Legg–Calvé–Perthes disease (LCPD) is a disorder in children were the head of the femur dies due to a lack of blood flow (avascular necrosis).[1] The most common symptom is a gradual onset of a limp.[1] Ability to move the leg may be deceased.[1] Pain is variably present and may occur in the hip, knee, or bum.[1] Both side are affected in up to 15% of cases.[1] Complications may include osteoarthritis.[1]
The cause is unknown but it is believed to involved multiple factors.[1][2] Proposed risk factors include genetics, hyperactivity, blood clotting problems, exposure to cigarette smoke, and extreme motion at the hip.[1][2] Diagnosis is by X-rays after ruling out other causes of osteonecrosis of the femoral head.[1]
There is no cure.[1] Treatments may include NSAIDs, decreasing physical activity, and physical therapy.[1] If these measures are insufficient surgery may be recommended.[1] Outcomes are usually good.[2]
The condition affects 1 in 1,200 people (1 to 21 per 100,000 people per year).[1][3] Those between the ages of 4 and 8 years are most commonly affected, but it can start at 18 months until growth stops.[1] Males are more commonly affected.[1] The first detailed description was in 1910 by Arthur Legg, Jacques Calvé, and Georg Perthesin.[1][2]
References[change | change source]
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 Karkenny, AJ; Tauberg, BM; Otsuka, NY (September 2018). "Pediatric Hip Disorders: Slipped Capital Femoral Epiphysis and Legg-Calvé-Perthes Disease". Pediatrics in review. 39 (9): 454–463. doi:10.1542/pir.2017-0197. PMID 30171056.
- ↑ 2.0 2.1 2.2 2.3 2.4 Leroux, J; Abu Amara, S; Lechevallier, J (February 2018). "Legg-Calvé-Perthes disease". Orthopaedics & traumatology, surgery & research : OTSR. 104 (1S): S107–S112. doi:10.1016/j.otsr.2017.04.012. PMID 29155310.
- ↑ 3.0 3.1 Mills, S; Burroughs, KE (January 2020). "Legg Calve Perthes Disease (Calves Disease)". PMID 30020602.
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