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Osteoarthritis

From Simple English Wikipedia, the free encyclopedia
An X-ray image of a knee with osteoarthritis.

Osteoarthritis normally affects older people. It is a disease where joints wear out. As the joint surface wears away, it sheds particles which stimulate the joint lining to produce fluid. This causes the joint to swell. When the joint cartilage wears away, the core of the bone becomes exposed. The exposed bone rubs against other exposed bone.

Synovial fluid analysis

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Synovial fluid examination[1][2]
TypeWBC (per mm3)% neutrophilsViscosityAppearance
Normal<2000HighTransparent
Osteoarthritis<5000<25HighClear yellow
Trauma<10,000<50VariableBloody
Inflammatory2,000–50,00050–80LowCloudy yellow
Septic arthritis>50,000>75LowCloudy yellow
Gonorrhea~10,00060LowCloudy yellow
Tuberculosis~20,00070LowCloudy yellow
Inflammatory: Arthritis, gout, rheumatoid arthritis, rheumatic fever

Management

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Exercise

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Weight loss and exercise give long-term treatment.[3] Short-term treatments usually have risk of harm (in the long-term).[4] The way to get through the pain is to be active (exercise), not rest. This is similar to the management of back pain, but other conditions require rest.

Symptoms

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Joints will be stiff and painful, and may be swollen. The pain may be worse after exercise. It may get harder to move the joint.

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References

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  1. Flynn JA, Choi MJ, Wooster DL (2013). Oxford American Handbook of Clinical Medicine. US: OUP. p. 400. ISBN 978-0-19-991494-4.
  2. Seidman AJ, Limaiem F (2019). "Synovial Fluid Analysis". StatPearls. StatPearls Publishing. PMID 30725799. Retrieved 2019-12-19.
  3. Hunter DJ, Eckstein F (2009). "Exercise and osteoarthritis". Journal of Anatomy. 214 (2): 197–207. doi:10.1111/j.1469-7580.2008.01013.x. PMC 2667877. PMID 19207981.
  4. Charlesworth J, Fitzpatrick J, Orchard J (2019). "Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee". BMC Musculoskeletal Disorders. 20 (1): 151. doi:10.1186/s12891-019-2525-0. PMC 6454763. PMID 30961569.