Raymond Gosling (15 July 1926 – 18 May 2015) was a British biophysicist. He was known for doing X-ray diffraction studies on DNA. These studies were the first step in understanding the 3-D structure of DNA. He did these studies as a doctoral student in the research group headed by Maurice Wilkins at Kings College London.
Gosling's first supervisor was A.R. Stokes of the Physics Department. By 1950, Gosling's diffraction photographs were described by Wilkins at the time as "much better than Astbury's, and almost like single crystals".
Gosling was re-assigned to Rosalind Franklin when she joined Wilkins' group in 1951. For the next two years, they worked closely together to improve the X-ray diffraction photography of DNA and get a sharper image. Gosling made the X-ray diffraction image of DNA known as "Photo 51". This work led directly to the 1963 Nobel Prize in Physiology or Medicine being awarded to Francis Crick, James D. Watson and Maurice Wilkins. Gosling was the co-author with Franklin of one of the three DNA double helix papers published in Nature in April 1953.
References[change | change source]
- Wilkins M; Gosling R. & Seeds W. 1951. "Physical studies of nucleic acid". Nature. 167 (4254): 759–760. Bibcode:1951Natur.167..759W. doi:10.1038/167759a0. PMID 14833383.
- Gosling R. et al 2011. "Seven ages of the PhD". Nature. 472 (7343): 283–286. doi:10.1038/472283a.
- Wilkins M.H.F. 1950. Letter to Markham, 15 June 1950, quoted in Olby, Robert 1974. The path to the double helix. Seattle: Unversity of Washington Prss, 333/4. ISBN 0-295-95359-4
- "Due credit". Nature. 496: 270. 2013. doi:10.1038/496270a.
- Franklin R.E. & Gosling R.G. 1953. "Molecular configuration in sodium thymonucleate". Nature. 171 (4356): 740–741. doi:10.1038/171740a0. PMID 13054694.
- Professor Raymond Gosling
Other websites[change | change source]
- Detailed interview 2013 in Genome Biology
- Raymond Gosling in The King's story
- Doppler-shifted ultrasound units (1974-1981) jointly developed by Dr.B.A.Coghlan and Prof.R.G.Gosling's Blood Flow Group at the Physics Dept., Guy's Hospital Medical School, London. These early devices were used for haemodynamic assessment of normal volunteers and assessment of patients with peripheral vascular disease. The work reflects a close and extensive collaboration with Dr.M.G.Taylor.