15 December 1916|
|Died||5 October 2004
Blackheath, London, England
|Known for||X-ray diffraction, DNA|
|Awards||Nobel Prize in Physiology or Medicine (1962)|
|Fields||Physics, Molecular biology|
|Institutions||University of California, Berkeley
King's College London
In recognition of this work, he, Francis Crick and James Watson were awarded the 1962 Nobel Prize in Physiology or Medicine, "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". His obituary provides extensive information on the topics mentioned here.
Wilkins was the Assistant Director of the Biophysics Unit at Kings College, and responsible for work on the structure of DNA. Wilkins and a graduate student, Raymond Gosling, got the first X-ray diffraction photos of DNA in 1950. He introduced Francis Crick to the importance of DNA, and hired Rosalind Franklin on a three-year grant. Franklin made progress with the crystallography, and produced some better photographs of the structure.
In 1953 Watson visited King's, and Crick got sight of a progress report. This report included useful information from Franklin about features of DNA she had deduced from her X-ray diffraction data.
Watson and Crick published their proposed DNA double helix structure in a paper in the journal Nature in April 1953. In this paper Watson and Crick acknowledged that they had been "stimulated by.... the unpublished results and ideas" of Wilkins and Franklin.
By this time Franklin was suffering from cancer of the ovary. She died in 1958, which explains why she was not included in the 1962 Nobel Prize. A controversy exists as to the relative contributions of her and Wilkins.
References[change | change source]
- The Nobel Prize in Physiology or Medicine 1962. Nobel Prize Site for Nobel Prize in Physiology or Medicine 1962.
- S. Arnott, T.W.B. Kibble and T. Shallice, Maurice Hugh 2006. Frederick Wilkins CBE: 15 December 1916-5 October 2004. Biographical Memoirs of Fellows of the Royal Society, 456--478.