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June 23, 1925|
Halifax, West Riding of Yorkshire, England
|Died||January 10, 2017
Chapel Hill, North Carolina, United States
|Alma mater||Balliol College, University of Oxford|
|Known for||Gel electrophoresis, gene targeting|
|Awards||Nobel Prize in Physiology or Medicine (2007)|
|Institutions||University of Toronto
University of Wisconsin–Madison
University of North Carolina at Chapel Hill
Much later, he worked on the technique of homologous recombination of transgenic DNA with genomic DNA. This is the most reliable method of altering animal genomes at present, and the technique behind gene targeting and knockout mice.
References[change | change source]
- "The Nobel Prize in Physiology or Medicine 2007". The Nobel Foundation. Retrieved 2007-10-08.
- Smithies, Oliver (1955-12). "Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults". The Biochemical Journal 61 (4): 629–641. ISSN 0264-6021. PMC 1215845. PMID 13276348. https://www.ncbi.nlm.nih.gov/pubmed/13276348. Retrieved 2009-08-04.