The Russian Soyuz program, the American Space Shuttle and the International Space Station are examples of manned missions. (Manned means the spacecraft has humans on board.) On the other hand, examples of unmanned flights are space probes which fly into deeper space, and satellites which travel around and orbit the Earth or other planets. (Unmanned means the spacecraft does not have any people on board.) Space probes and satellites are both machines that work either by radio control from Earth or are fully automatic.
Spaceflight is used for space exploration such as manned missions to the Earth's moon or unmanned missions to other planets in the solar system. Spaceflight can also be used for tourism and satellite telecommunications. A spaceflight begins with a rocket launch, which provides enough energy to get out of Earth's atmosphere and to orbit the Earth. Once the rocket is in space, the activity of the rocket is watched and studied by scientists back on Earth. Some rockets may remain in space forever, some break apart when they re-enter Earth's atmosphere. Some spacecraft are made to land on other planets, and most manned spacecraft are made to land back on Earth, most of the time using a parachute to land safely.
On October 3, 1942, a German V-2 missile crossed the Kármán line (100 km or 62 miles above the Earth) on October 3, 1942. This was the first spaceflight. The first man-made satellite to travel around Earth was the Russian Sputnik 1 on October 4, 1957.