Thiamine

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Thiamine
Thiamin.svg
Thiamine cation 3D ball.png
Skeletal formula and ball-and-stick model of the cation in thiamine
Clinical data
Pronunciation/ˈθ.əmɪn/ THY-ə-min
SynonymsVitamin B1, aneurine, thiamin
AHFS/Drugs.comMonograph
License data
Routes of
administration
by mouth, IV, IM[1]
Drug classvitamin
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability3.7% to 5.3% Template:Medical citation needed
Elimination half-life1.8d[2][better source needed]
Identifiers
  • 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
CAS Number
PubChem CID
PubChem SID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC12H17N4OS+
Molar mass265.36 g·mol−1
3D model (JSmol)
  • cation: Cc2ncc(C[n+]1csc(CCO)c1C)c(N)n2
  • cation: InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1 checkY
  • Key:JZRWCGZRTZMZEH-UHFFFAOYSA-N

Thiamine (or thiamin) is vitamin B1. It is a water-soluble vitamin of the B complex. Its phosphate derivatives take part in many cellular processes. Thiamine pyrophosphate (TPP) is a coenzyme in the catabolism of sugars and amino acids.

also it can be found in Food and Manufactured Dietary supplements also in Medications[1][3] Foods that provide Thiamine include whole grains, Legume[1]

Lack of thiamine causes beriberi.

References[change | change source]

  1. 1.0 1.1 1.2 "Thiamin Fact Sheets for Health Professionals". Office of Dietary Supplements. 11 February 2016. Archived from the original on 30 December 2016. Retrieved 30 December 2016.
  2. Royer-Morrot MJ, Zhiri A, Paille F, Royer RJ (1992). "Plasma thiamine concentrations after intramuscular and oral multiple dosage regimens in healthy men". European Journal of Clinical Pharmacology. 42 (2): 219–22. doi:10.1007/BF00278489. PMID 1618256. S2CID 19924442.
  3. "Thiamine: MedlinePlus Drug Information". medlineplus.gov. Retrieved 30 April 2018.