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|'SpongeBob SquarePants' character|
|First appearance||Plankton! (July 31, 1999)|
|Portrayed by||Jill Talley|
|Relatives||Husband: Sheldon J. Plankton|
Son: Chip Plankton II
Karen Plankton is one of the main characters of SpongeBob SquarePants. She is a waterproof supercomputer who lives in the Chum Bucket laboratory. She is Plankton's wife and sidekick to steal the secret formula of the Krabby Patty. Karen's name is based on Hillenburg's wife Karen Hillenburg.
Karen first appeared in the episode "Plankton!" along with Plankton on July 31, 1999.