Pyrimidine

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Pyrimidine
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IUPAC name Pyrimidine
Other names 1,3-Diazine, m-Diazine
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Pyrimidines include three of the bases in DNA and RNA.

A pyrimidine is an aromatic heterocyclic organic compound, similar to purine.[1] It has nitrogens at positions 1 and 3 in the ring.[2][3]

Pyrimidines[change | change source]

The pyrimidine ring system occurs widely in nature.[4]

It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Uric acid is a pyrimidine derivative.

References[change | change source]

  1. Gilchrist T.L. (1997). Heterocyclic chemistry. New York: Longman. ISBN 0-582-27843-0. 
  2. Joule, John A.; Mills, Keith, eds. (2010). Heterocyclic chemistry (5th ed.). Oxford: Wiley. p. 250. ISBN 978-1-405-13300-5. 
  3. Brown H.C. et al 1955. In Baude, E.A. and Nachod, F.C., Determination of organic structures by physical methods. Academic Press, New York.
  4. Lagoja, Irene M. (2007). "Pyrimidine as constituent of natural biologically active compounds". Chemistry and Biodiversity 2 (1): 1–50. doi:10.1002/cbdv.200490173. PMID 17191918. http://homepage.univie.ac.at/mario.barbatti/papers/pyrazine_pyrimidine/pyrimidine.pdf.