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Systematic (IUPAC) name
CAS number 50-53-3 (free base)
69-09-0 (hydrochloride)
ATC code N05AA01
PubChem 2726
DrugBank DB00477
ChemSpider 2625
Chemical data
Formula C17H19ClN2S 
Mol. mass 318.86 g/mol (free base)
355.33 g/mol (hydrochloride)
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability Oral, 30 to 50% (interindividual variations 10–70%)
Metabolism Hepatic, mostly CYP2D6-mediated
Half life 16 to 30 hours. In long term treatment, CPZ induces its own metabolism
Excretion Biliary and renal, as metabolites (only traces of unchanged drug)
Therapeutic considerations
Pregnancy cat.

C—only when benefit for the mother exceeds risk to unborn child

Legal status

Prescription only

Routes Oral, rectal (suppository), IM, IV infusion

Chlorpromazine is an antipsychotic drug. It is the oldest such drug. It was developed in 1950. It is typically used to treat Schizophrenia. It has also been used to treat bipolar disorder. It has been shown to help uncontrollable hiccups disappear. It is also used to help with nausea and vomiting.