From Simple English Wikipedia, the free encyclopedia

Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.

Many neurodegenerative diseases – including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease.

Such diseases are incurable, resulting in progressive degeneration and/or death of neuron cells.[1]

There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death.[2][3] Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.

References[change | change source]

  1. "What is Neurodegenerative Disease?". JPND Research. JPND Research. 17 July 2014. Retrieved February 7, 2015.
  2. Rubinsztein DC (October 2006). "The roles of intracellular protein-degradation pathways in neurodegeneration". Nature. 443 (7113): 780–6. Bibcode:2006Natur.443..780R. doi:10.1038/nature05291. PMID 17051204. S2CID 4411895.
  3. Bredesen DE, Rao RV, Mehlen P (October 2006). "Cell death in the nervous system". Nature. 443 (7113): 796–802. Bibcode:2006Natur.443..796B. doi:10.1038/nature05293. PMC 3970704. PMID 17051206.